School of Mechanical, Materials and Mechatronic Engineering
SEMINAR Cell Encapsulation for Multiplexing Diagnostic Assays Using Novel Centrifugal Microfluidic Emulsification and Separation Platform
PRESENTER Dr Yong Reng WHERE BLD 8.G25 DATE Thursday 2nd of June 2016 TIME 12:30 - 13.30
ABSTRACT A novel centrifugal microfluidic platform for emulsification and separation will be presented. The platform enables encapsulation and incubation of multiple types of cells by microdroplets, which can be generated at controlled high rotation speed. The droplets can be separated from continuous phase using facile bifurcated junction design. A three dimensional model was established to investigate the formation and sedimentation of droplets using the centrifugal microfluidic platform by computational fluid dynamics. The physics associated with droplet formation and sedimentation is governed by the Bond number and Rossby number, respectively. Our investigation provides insight into the design criteria that can be used to establish centrifugal microfluidic platforms tailored to potential applications, such as multiplexing diagnostic assays, due to the unique capabilities of the device in handling multiple types of cells and biosamples with high throughput. This work can inspire new development of cell encapsulation and separation applications by centrifugal microfluidic technology.
ABOUT THE SPEAKER Dr Yong Ren is Assistant Professor with the Department of Mechanical, Materials, and Manufacturing Engineering at University of Nottingham Ningbo China (UNNC). He received BEng degree from Beihang University and PhD degrees from Hong Kong Polytechnic University. His PhD research focuses on centrifugal microfluidic flow and mixing with applications in cell culture and cell lysing, and the research can lead to automated bio-sample preparation and nucleic acid analysis for lab-on-a-chip applications. Prior to joining UNNC in 2013, he had worked as postdoctoral research associate at microfluidics and soft matter group of University of Hong Kong. His research interest focuses on microscale multiphase flow dynamics, heat and mass transfer, bio-MEMS device fabrication, synthesis of functional materials for biomedical applications and sustainable development. He has been principal investigator of three research projects funded by National Natural Science Foundation of China, Zhejiang Natural Science Foundation and Ningbo Natural Science Foundation, respectively. He is member of ASME and reviewer of several international journals.
Department of Mechanical, Materials, and Manufacturing Engineering University of Nottingham Ningbo China 199 Taikang East Road, Ningbo 315100 China Tel: 86-0574-88189064 Email: firstname.lastname@example.org
Following the seminar, you are all welcome to join Dr Yong Reng for lunch and further discussion which will be held in Foyer 8.124 at 1.30pm. ?
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